Toups is a French surname found in Cajun communities. Notable people with the surname include:

Alzina Toups (1927–2022), American chef David Toups (born 1971), American bishop of the Diocese of Beaumont, Texas Judith Toups (1930–2007), American birder and columnist Mary Oneida Toups (1928–1981), American occultist Wayne Toups (born 1958), American Cajun singer