Oxus may refer to:

Oxus River, also called the Amu Darya, Amu or Amo River, a major river in Central Asia. Oxus valley (disambiguation) Oxus civilization, a bronze age civilization of central Asia Oxus (god), an Eastern Iranian god regarded as the personification of the Amu Darya Oxus cobra, also known as the Caspian cobra, Central Asian cobra, or Russian cobra Oxus (mite), a genus of mite in the family Oxidae

See also Oxus Treasure Transoxiana