The 1919 Washington University Pikers football team represented Washington University in St. Louis as a member of the Missouri Valley Conference (MVC) during the 1919 college football season. In its third and final season under head coach Dick Rutherford, the team compiled a 5–2 record (2–2 against MVC opponents), tied for third place in the conference, and outscored opponents by a total of 127 to 30.

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