Tselios () is a surname. Notable people with the surname include:
Alexandra Tselios, Australian entrepreneur, social commentator and business columnist Athanasios Tselios (born 1956), Greek retired Hellenic Army officer Ilias Tselios (born 1997), Greek footballer Nikos Tselios (born 1979), American professional ice hockey player Paraskevas Tselios (born 1997), Greek male volleyball player