Delio may refer to:
Given name Delio Caron (born c. 1924), Italian rugby player Délio dos Santos (died 2020), Brazilian politician Delio Fernández (born 1986), Spanish cyclist Delio Gamboa (1936–2018), Colombian footballer Delio Hernández Valadés (born 1956), Mexican politician Delio Morollón (1937–1992), Spanish footballer Delio Rodríguez (1916–1994), Spanish road racing cyclist and sprinter Delio Rossi (born 1960), Italian football manager and former footballer Delio Onnis (born 1948), Italian-Argentine footballer Delio Tessa (1886–1939), Italian poet Delio Toledo (born 1976), Paraguayan footballer
Surname Michelle Delio, American journalist and writer Thomas DeLio (born 1951), American experimental music composer
See also Delio Lake, is a lake in the Province of Varese, Lombardy, Italy