Nsubuga is a surname. Notable people with the surname include:
Dunstan Nsubuga, Anglican bishop in Uganda Emmanuel Nsubuga (1914–1991), Ugandan Roman Catholic archbishop Emmanuel Nsubuga (boxer) (born 1967), Ugandan boxer Eridard Nsubuga, Anglican bishop in Uganda Florence Nsubuga (born 1973), Ugandan businesswoman Frank Nsubuga (born 1980), Ugandan cricketer Kipoi Tonny Nsubuga (born 1978), Ugandan politician