The 1901 Wesleyan Methodists football team represented Wesleyan University as a member of the Triangular Football League (TFL) during the 1901 college football season. In their third season under head coach Robert P. Wilson, the Methodists compiled an overall record of 3–6–1 with a mark of 1–1 in conference play, placing second in the TFL. The team played home games at Andrus Field in Middletown, Connecticut.

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