Siege of Nisibis may refer to: Siege of Nisibis (197) by the Parthians under Vologases V Siege of Nisibis (235) Siege of Nisibis (252) by the Sassanids under Shapur I Siege of Nisibis (262) by the Romans under Odaenathus Siege of Nisibis (338) by the Sassanids under Shapur II Siege of Nisibis (346) by the Sassanids under Shapur II Siege of Nisibis (350) by the Sassanids under Shapur II Siege of Nisibis (573)

See also Battle of Nisibis (disambiguation)