DeMeo is a surname. Notable people with the surname include:
Adriana DeMeo (born 1981), American actress Bob DeMeo (1955-2022), American musician Roy DeMeo (1940–1983), Italian-American mobster Tony DeMeo (born 1948), American football coach William DeMeo (born 1971), American actor, producer, director, and writer
See also Dameo Demeo