Fragoso is a surname. Notable people with the surname include:
António Fragoso (1897–1918), Portuguese composer and pianist. Daniel Fragoso (born 1982), Spanish footballer Heleno Fragoso (1926–1985), Brazilian criminologist Ignacio Fragoso (born 1968), Mexican long-distance runner Javier Fragoso (1942–2014), Mexican former football player and manager Juan de Matos Fragoso (c. 1608-1689?), Spanish dramatist Margaux Fragoso (1979–2017), American memoirist Thiago Fragoso (born 1981), Brazilian actor, voice actor and singer Valdemar Gutiérrez Fragoso (born 1956), Mexican politician Lubelia Maria Furtado Fragoso (born 1967), Civic activist