Antimachia () was a town of ancient Greece on the island of Cos.Plutarch, Greek Questions, Moralia § 58. Antimachia was the capital of the demoi of AegelusW. R. Paton and E. L. Hicks The Inscriptions[WS 1] of Cos nr. 393 & 394; and Archia.

Its site is located near modern Antimakheia.

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