Astypalaea or Astypalaia () was a town of ancient Greece on the island of Samos according to Stephanus of Byzantium, said by others to be either the acropolis of the city of Samos,Polyaen. Strat. 1.23.2 or the name of half of the city.Etymologicum Magnum
The town is presumably on the mountain of the same name which modern scholars have located on Samos.
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