Mettler is a German surname. Notable people with the surname include:
Barbara Mettler (born 1971), Swiss cross country skier
Bill Mettler (born 1946), American swimmer Cecilia Mettler, American medical historian Dölf Mettler (1934–2015), Swiss yodeler, composer and painter Jim Mettler, American politician Liselotte Mettler, Austrian-German surgeon Melanie Mettler (born 1977), Swiss politician Nemo Mettler (born 1999), Swiss singer Peter Mettler (born 1958), Swiss-Canadian film director and cinematographer Ruben F. Mettler (1924–2006), American businessman Suzanne Mettler, American political scientist and author Yannick Mettler (born 1989), Swiss racing driver
See also Mettler (disambiguation)