Soffici is a surname. Notable people with the surname include:
Ardengo Soffici (1879–1964), Italian writer, painter, poet, sculptor and intellectual Filippo Soffici (born 1970), Italian rower Juan Soffici, Argentine film editor Mario Soffici (1900–1977), Italian-born Argentine film director, actor and screenwriter Piero Soffici (1920–2004) Italian composer and conductor Roberto Soffici (born 1946), Italian singer-songwriter, composer and lyricist