Petacci is a surname. Notable people with the surname include:
Clara Petacci (1912–1945), mistress of Benito Mussolini Marcello Petacci (1910–1945), Italian surgeon and businessman and brother of Clara Maria Petacci (1923–1991), Italian actress, known as Miriam di San Servolo, and sister of Clara Emilio Petacci (1886–1965), Italian film actor