Wyeth is a surname. Notable people with the name include:
N. C. Wyeth (1882–1945), American artist, or one of his family: daughter Henriette Wyeth (1907–1997), artist daughter Carolyn Wyeth (1909–1994), artist son Nathaniel C. Wyeth (1911–1990), mechanical engineer and inventor grandson Howard Wyeth (1944–1996), drummer and pianist daughter Ann Wyeth McCoy (1915–2005), artist son Andrew Wyeth (1917–2009), artist grandson Jamie Wyeth (born 1946), artist Adam Wyeth (born 1978), English poet, playwright and essayist Alison Wyeth (born 1964), English long-distance runner Arthur Wyeth (1887–1971), Australian cricket umpire Ezra Wyeth (1910–1992), Australian cricketer Huston Wyeth (1863–1925), American businessman John Wyeth (1770–1858), American publisher John Allan Wyeth (1845–1922), American Confederate veteran and surgeon Joseph Wyeth (1663–1731), English Quaker merchant Joshua Wyeth (1758-1829), Blacksmith Apprentice, American Patriot, Participated in and later coined the phrase "Boston Tea Party" Katya Wyeth (born 1948), German-born American model and actress Marion Sims Wyeth (1889–1982), American architect Nathan C. Wyeth (1870–1963), American architect, designer of the Oval Office and West Wing Nathaniel Jarvis Wyeth (1802–1856), American inventor, ice harvester, explorer and trader Steven Wyeth, British football commentator