Randazzo is a surname. Notable people with the surname include:
Filippo Randazzo, 18th-century Italian painter Filippo Randazzo (athlete) (born 1996), Italian long jumper Florencio Randazzo (born 1964), Argentine politician Joe Randazzo (born 1978), American comedian and newspaper editor Matthew Randazzo V (born 1984), American true crime writer and historian Nino Randazzo (born 1932), Italian Australian politician Teddy Randazzo (1935–2003), American pop songwriter