CS2 may refer to:

Software and video games Counter-Strike 2, a 2023 first-person shooter computer game Cities: Skylines II, a 2023 city management computer game CS2, Adobe Creative Suite's second version, a graphic software suite

Chemistry

Carbon disulfide, CS2, an inorganic compound Dicaesium, Cs2, an allotrope of elemental caesium CS2, a siliconized, micro-pulverized form of CS gas

See also CS2, the former name of a cycle route in London, now known as C2 CS-2, a supercomputer system architecture by Meiko Scientific

, a Wikipedia project page