Domeros was a settlement in ancient Macedonia, which in the time of the Roman Empire, had a mutatio, or place for changing horses, on the Via Egnatia. It was situated between Amphipolis and Philippi, 13 M. P. from the former and 19 M. P. from the latter.Itin. Hierosol.; comp. Tafel, de Via Egnat. p. 10.

The site of Domeros is near the modern Domiros.

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