John Maddox (1925–2009) was a British scientist.
John Maddox may also refer to:
John Maddox (cricketer) (born 1930), Australian former cricketer John Maddox (politician), American politician Johnny Maddox (1927–2018), American ragtime pianist John Medex Maddox (1789–1861), British playwright and theatre manager John W. Maddox (1848–1922), U.S. Representative from Georgia