Potosino is a demonym associated with San Luis Potosí City, San Luis Potosi, Mexico. It may refer to:
Atlético Potosino, a football team Autódromo Potosino, a racecourse Club Deportivo Potosino, a sports club FC Potosino, a football team Instituto Potosino de Investigación Científica y Tecnológica, the San Luis Potosí Institute of Scientific Research and Technology Instituto Potosino Marista, a K-12 Marist Brothers school