Hupp is a surname. Notable people with the surname include:
Anne Hupp (1757–1823), American frontierswoman Bobby Hupp (1877–1931), American automobile engineer and company founder Harry Lindley Hupp (1929-2004), American judge Jana Marie Hupp (born 1964), American actress Otto Hupp (1859–1949), German graphical artist Pam Hupp (born 1957/1958), American woman charged with murder Suzanna Hupp (born 1959), American politician