The 2005–06 season of the Divizia A Feminin was the 16th season of Romania's premier women's football league. Two divisions (West/South) with four teams each played a double round robin. First two places in each division qualified in the Championship play-off (4 teams playing a single round-robin). Clujana won the title.

Championship play-off CFF Clujana (champion 2006–07 UEFA Women's Cup Qualifying round) Pandurii Lignitul Târgu Jiu CSS Târgovişte Motorul Oradea

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