Mystic Marriage of Saint Catherine is an oil-on-panel painting by Italian Renaissance artist Lorenzo Lotto, painted ca. 1506–1508. It is signed on Catherine of Alexandria's broken wheel (centre foreground) "Laurent.[ius] Lotus F.[ecit]". The painting is known to have moved from the Würzburg Residence to the Hofgartengalerie in 1804 and then to its present home in the Alte Pinakothek in Munich.Carlo Pirovano, Lotto, Electa, Milano 2002.

A workshop version of the painting is in the Museum of Fine Arts, Boston.

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