Wissler is a surname. Notable people with the surname include:
Clark Wissler (1870–1947), American anthropologist Janina Wissler (born 1983), German model, actress and television host Janine Wissler (born 1981), German politician John Wissler, American lieutenant general Susan Wissler (1853–1939), American politician
See also Susan Wissler House Wissler's syndrome