Homberger is a surname. Notable people with the surname include:
Alex Homberger (1912–2007), Swiss rower Daniel Homberger (born 1955), Swiss rower Dominique G. Homberger (born 1948), American zoologist Ernst Homberger (1869–1955), Swiss industrialist Esther Fischer-Homberger (1940–2019), Swiss psychiatrist and medical historian Hans Homberger (1908–1986), Swiss rower Rudolf Homberger (1910–?), Swiss rower