Tame is a surname. Notable people with the surname include:
Chris Tame (1949–2006), British libertarian political activist David Tame (born 1953), British author Grace Tame (born 1994), Australian activist and 2021 Australian of the Year Jack Tame (born 1987), New Zealand television and radio journalist John Tame (c. 1430-1500), British merchant Johnny Tame (1947–2022), German singer songwriter and guitarist Kevin Tame (1931–1995), Australian rules footballer Michael Tame (born 1956), Australian cricketer