The 1980 Kilkenny Senior Hurling Championship was the 86th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board in 1887.

Ballyhale Shamrocks were the defending champions.

On 2 November 1980, Ballyhale Shamrocks won the championship after a 3–13 to 1–10 defeat of Muckalee/Ballyfoyle Rangers in the final replay. It was their third championship title overall and their third title in succession.

Results Group 1 Table

TeamMatchesScorePtsPldWDLForAgainstDiffMuckalee/Ballyfoyle Rangers651013-756-504611Fenians65107-776-413911Erin's Own630310-639-5796Galmoy630317-4714-58-26Conahy Shamrocks63039-558-5446Bennettsbridge610510-3611-63-302Windgap60069-4821-77-710

Group 2 Table

TeamMatchesScorePtsPldWDLForAgainstDiffBallyhale Shamrocks64209-6714-401210James Stephens641111-6211-44189Rower-Inistioge633019-5014-47189St. Patrick's622220-5214-6196O'Loughlin Gaels620414-539-6354St. Lachtain's62049-6314-54-62Mooncoin600611-3027-68-860

Play-offs

Quarter-finals

Semi-finals

Final

References