Colwell is an English surname. Notable people with the surname include:

Anna Colwell (1876–1941), American politician Bob Colwell (born 1954), American electrical engineer Carlton H. Colwell (1926–2021), American politician Dave Colwell (born 1964), English rock guitarist Eileen Colwell (1904–2002), English librarian Elizabeth Colwell (1881–1954), American printmaker, typographer and writer Ernest Cadman Colwell (1901–1974), American biblical scholar, textual critic and palaeographer Frederick Colwell (fl. 1970s–2020s), American microbiologist Guy Colwell (born 1945), American painter and cartoonist Jack Colwell (1989–2024), Australian singer-songwriter James Colwell (1860–1930), English-born Australian Methodist minister and historian Jason Colwell (born 1974), Irish footballer Jeffrey Colwell (born 1965), American lawyer Keith Colwell (born 1947), Canadian politician Maria Colwell (1965–1973), British female murder victim Oliver Colwell (1834–1862), Union Army officer and Medal of Honor recipient Otis Colwell (born c. 1797), American merchant and politician Patrick Colwell (born c. 1951), American politician Rita R. Colwell (born 1934), American environmental microbiologist and scientific administrator

See also Jane Colwell-Danis (born 1941), American paleontologist