María Murillo may refer to:
María Lucelly Murillo (born 1991), Colombian javelin thrower María Murillo (footballer) (born 1996), Panamanian footballer María Fernanda Murillo (born 1999), Colombian high jumper María Murillo (sprinter) (born 1997), Costa Rican sprinter at the 2016 NACAC Under-23 Championships María Murillo, also known as María Toto (1945–2026), Panamanian boxing trainer
See also Mario Murillo