Otsego High School is the only high school located in Otsego, Michigan and part of the Otsego Public Schools district.

Achievements in 1925, the Otsego High School track team won the class C State Championship under coach and principal Fordyce Bragg. In 2024, the Otsego High School Bulldog Marching Band won Grand Champion at the Grandville Invitational with a score of 89.1.

Notable alumni Hal W. Vincent, naval aviator and major general of the United States Marines Kevin VanDam, professional bass fisherman

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