Caltagirone () is an Italian surname that may refer to Daniel Caltagirone (born 1972), English actor Francesco Bellavista Caltagirone (born 1939), Italian businessman, entrepreneur and philanthropist Francesco Gaetano Caltagirone (born 1943), Italian businessman, cousin of Francesco Bellavista Caltagirone Editore, an Italian publishing house founded by Francesco Gaetano Thomas Caltagirone (born 1942), American politician