Zakare I Zakarian or Zakaria I Mkhargrdzeli was Armenian landholder in Kingdom of Georgia and vassal of Orbeli family during the 12th century. Javakhishvili, Ivane (1965-1966), k'art'veli eris istoria (The History of the Georgian Nation), vol. 2-3. Tbilisi State University Press.Джанашиа С. Н., Об одном примере искажения исторической правды..., Тб., 1947; He belonged to the Zakarids–Mkhargrdzeli line.

He was the chief patron of the Haghpat Monastery.

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