George Wise may refer to:
George Wise (Australian politician) (1853–1950), Australian politician and solicitor George Wise (rugby union) (1904–1971), New Zealand rugby union player George D. Wise (general) (1816–1881), Union Army officer during the American Civil War George D. Wise (politician) (1831–1898), U.S. Representative from Virginia George S. Wise (1906–1987), American Jewish sociologist