Cobelli is an Italian surname. Notable people with the surname include:
Giancarlo Cobelli (1929–2012), Italian actor and stage director (1936–2019), Italian actor Giovanni Cobelli (1849–1937), Italian civil servant and naturalist Giuseppina Cobelli (1898–1948), Italian opera singer Juan Manuel Cobelli (born 1988), Argentine footballer (c. 1425–1500), Italian painter and historian Ruggero Cobelli (1838–1921), Italian entomologist Sebastián Cobelli (born 1978), Argentine footballer