The men's 4 × 100 metre medley relay competition at the 2018 Pan Pacific Swimming Championships took place on August 12 at the Tokyo Tatsumi International Swimming Center. The defending champion was the United States.

Records Prior to this competition, the existing world and Pan Pacific records were as follows: World recordAaron Peirsol (52.19)Eric Shanteau (58.57)Michael Phelps (49.72)David Walters (46.80)3:27.28Rome, Italy2 August 2009Pan Pacific Championships recordMatt Grevers (53.10)Kevin Cordes (58.64)Michael Phelps (50.60)Nathan Adrian (47.60)3:29.94Gold Coast, Australia24 August 2014

Results All times are in minutes and seconds.

KEY:CRChampionships recordNRNational recordPBPersonal bestSBSeasonal best

Final The final was held on 12 August from 18:00. Rank Lane Nation Swimmers Time Notes 4 Ryan Murphy (52.70)Andrew Wilson (59.15)Caeleb Dressel (50.64)Nathan Adrian (47.71)3:30.20 5 Ryosuke Irie (52.61)Yasuhiro Koseki (58.62)Yuki Kobori (51.19)Katsumi Nakamura (47.83)3:30.25 3 Mitch Larkin (53.18)Jake Packard (59.03)Grant Irvine (51.40)Kyle Chalmers (46.91)3:30.52 4 6 Gabriel Fantoni (53.72)João Gomes Júnior (59.05)Vinicius Lanza (51.68)Pedro Spajari (47.71)3:32.16 5 2 Javier Acevedo (54.05)Richard Funk (59.79)Josiah Binnema (52.25)Yuri Kisil (48.11)3:34.20 6 7 Armand Chan (1:02.06)Timothy Yen (1:08.46)Jarod Hatch (55.31)Rafael Barreto (52.93)3:58.76

References