Lopamudra was a female philosopher according to ancient Vedic Indian literature.

Lopamudra may also refer to:

Lopamudra Bhattacharji (born 1960), Indian cricketer Lopamudra Mitra, Bengali singer Lopamudra Raut (born 1991), Indian model and actress Lopamudra, a 1930 novel by Kanaiyalal Maneklal Munshi