Iyambo is a surname. Notable people with the name include:

Abraham Iyambo (1961–2013), Namibian politician Nickey Iyambo (born 1936), Namibian politician and physician Patrick Iyambo (1939–1991), Namibian politician

See also Dr Abraham Iyambo Senior Secondary School, is a school in the Ohangwena Region of northern Namibia