Serre di Rapolano is a frazione in the comune of Rapolano Terme in the province of Siena, Tuscany, Italy.
It is located on a hill midway between the valleys of the Sentino and Ombrone rivers. Among the prominent buildings are: Palazzo Gori Martini, a 19th-century neo-Gothic white marble palace Chiesa della Compagnia di Santa Caterina della Misericordia, a small oratory with frescoes by Sebastiano Follia and canvases by Astolfo Petrazzi Castello di Modanella Pieve di Sant'Andreino alle Cave Pieve dei Santi Andrea e Lorenzo
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