Masella is a surname. Notable people with the surname include:
Alfons Masella, Tongan rugby league footballer Benedetto Aloisi Masella (1879–1970), Italian Cardinal of the Roman Catholic Church Blanca Morales-Masella (born 1970), Guatemalan swimmer Gaetano Aloisi Masella (1826–1902), Italian Cardinal of the Roman Catholic Church Joseph Masella ( 1948–1998), American mobster Joseph Masella (1925–1996), Canadian-French hornist and music educator Martin Masella (born 1969), Tongan rugby league footballer Tom Masella (born 1959), American football player and coach
See also Masella, ski resort in La Cerdanya in Girona