Mazariegos is a municipality located in the province of Palencia, Castile and León, Spain.
Mazariegos and de Mazariegos may also refer to:
People Surnamed Mazariegos Alexander Mazariegos (died 2012), Belizean shooting victim Andrés Mazariegos Vázquez (1932–2022), Spanish bullfighter, known as Andrés Vázquez or "El Nono" Fernando Mazariegos (1938–2018), Guatemalan inventor of the drinking water filter "Ecofilter" Pedro Molina Mazariegos (1777–1854), Central American politician, considered one of the founders of liberalism in Guatemala Rocael Mazariegos (born 1966), Guatemalan footballer Silvia Carolina Mazariegos (born 1961), Guatemalan Woman International Master in chess
Surnamed de Mazariegos Diego de Mazariegos (died 1536), Spanish conquistador Diego de Mazariegos Guadalfajara (16th century), colonial governor of Cuba and of Venezuela Province