Bob or Robert Wilkie may refer to:
Robert Wilkie (moderator) (1548–1611), moderator of the General Assembly of the Church of Scotland in 1600 and principal of St Andrews University, 1591–1611 Bob Wilkie (footballer) (1920–2001), Australian rules footballer Bob Wilkie (ice hockey) (born 1969), Canadian ice hockey player Robert Wilkie (born 1962), American lawyer and government official Robert Wilkie (cricketer) (1878–1966), New Zealand cricketer Robert J. Wilke (1914–1989), American actor