Hesam or Hessam may refer to:
People
Hessam Abrishami (born 1951), Iranian-American artist Hesam Fetrati (born 1981), Iranian artist Hesam Manzour (born 1980), Iranian actor Hessam Nowzari, American dentistry academic Salman Hesam (born 1947), Iranian Olympic athlete
Geography Mir Hesam, a village in Kurdistan Province, Iran Mirza Hesam, a village in West Azerbaijan Province, Iran
Other HESAM University Group, a group of French educational institutions