The following lists events that happened during 2018 in the Democratic Republic of São Tomé and Príncipe.

Incumbents President: Evaristo Carvalho Prime Minister: Patrice Trovoada (until 3 December); Jorge Bom Jesus (from 3 December)

Events 1 January: currency reform: 1,000 old dobras became one new São Tomé and Príncipe dobraReforma Monetária 2018, Central Bank of São Tomé and Príncipe 3 December – Jorge Bom Jesus takes over as prime minister.

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