Dermitzakis is a surname. Notable people with the surname include:
Emmanouil Dermitzakis (born 1972), Greek geneticist Giannis Dermitzakis (born 1992), Greek footballer Konstantinos Dermitzakis (born 1982), Greek footballer Manolis Dermitzakis (born 1976), Greek footballer Pavlos Dermitzakis (born 1969), Greek footballer