Elise Mertens defeated Aryna Sabalenka in the final, 7–5, 6–2, to win the singles title at the 2018 Ladies Open Lugano.

Markéta Vondroušová was the defending champion, but lost in the second round to Mertens.

Seeds

Draw

Finals

Top half

Bottom half

Qualifying

Seeds

Qualifiers

Lucky loser

Draw

First qualifier

Second qualifier

Third qualifier

Fourth qualifier

Fifth qualifier

Sixth qualifier

References

Main draw Qualifying draw