Nitsche is a surname. Notable people with the surname include:

Dominik Nitsche, German professional poker player Joachim Nitsche (1926–1996), German mathematician Erik Nitsche, American graphic designer Francisco Nitsche, Chilean footballer Franz Nitsche, Austrian rower Heino Nitsche (1949–2014), German-American nuclear chemist Hinrich Nitsche, German zoologist Paul Nitsche (1876–1948), German psychiatrist executed for crimes against humanity Robert Lehmann-Nitsche, German anthropologist

See also Friedrich Nietzsche, whose last name is sometimes misspelt "Nitsche". Nietzsche (disambiguation)