161 Squadron or 161st Squadron may refer to:
No. 161 Squadron RAF, a unit of the Royal Air Force No. 161 Squadron RCAF, a unit of Royal Canadian Air Force 161 Squadron (Israel) a unit of the Israeli Air Force 161st Intelligence Squadron, a unit of the United States Air Force VFA-161, a strike fighter unit of the United States Navy VMM-161, a tiltrotor transport unit of the United States Marine Corps