Senhouse is a surname, and may refer to:
Humphrey Senhouse (politician) (1731–1814), British Tory politician Humphrey Fleming Senhouse (1781–1841), British Royal Navy officer Richard Senhouse (died 1626), English Bishop of Carlisle Roger Senhouse (1899–1970), English publisher and translator William Senhouse (died 1505), English Bishop of Durham
See also John L. Senn House