Case file, or casefile, may refer to:

Media Canadian Case Files, a 2005 TV series about the investigation of unsolved crimes in Canada. Casefile, an Australian true crime podcast that first aired in January 2016

Music The Case Files, a 2011 compilation album by singer-songwriter Peter Case

Novels/comics Case Files: Sam & Twitch, part of the Sam and Twitch comic series, first published in 2013

Software L.A. Noire: The VR Case Files, a 2011 detective video game published by Rockstar Games Virtual Case File (VCF), an application developed by the FBI between 2000 and 2005

See also Case (disambiguation) Casebook (disambiguation)